专   业：

细胞生物学

姓   名：

辛凤姣

职   称：

研究员

研究领域：

生物技术

邮   箱：

2002hongzhi30@163.com

电   话：

010-62815873

主要社会兼职

1. 北京食品学会青年工作委员会副主任

2. 中国生物化学与分子生物学农业专业分会第九届委员会委员

3. Journal of Agriculture and Food Chemistry杂志编委

代表性论文

1. Shujun Liu#, Boting Wen#, Guoming Du, Yulu Wang, Xiaochen Ma, Haiyan Yu, Jingjian Zhang, Shilong Fan, Huan Zhou, Fengjiao Xin* Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH, Food Chemistry, 2023, 403: 134436 (IF:8.5)

2. Xue Wei#, Yulu Wang#, Su Zhang#, Tianyi Gu, Gabryel Steinmetz, Haiyan Yu, Guoguang Guo, Xin Liu, Shilong Fan, Fengzhong Wang, Yangnan Gu, Fengjiao Xin*, The Patrol Yeast: Structural analysis of receptor-like kinase SOBIR1 reveals mechanisms that regulate its phosphorylation-dependent activation. Plant Communications, 2022, 3: 100301 (IF: 10.5)

3. Lichao Sun, Fengjiao Xin*, Hal S. Alper*, Bio-synthesis of food additives and colorants-a growing trend in future food. Biotechnology Advances, 2021, 47: 107694 (IF: 16.0)

4. Zhen Li#, Lina Sun#, Yulu Wang, Bolin Liu, Fengjiao Xin* Construction of a Novel Vanillin-Induced Autoregulating Bidirectional Transport System in a Vanillin-Producing E. coli Cell Factory. Journal of Agricultural and Food Chemistry, 2024, 72(26): 14809-14820 (IF: 5.7)

5. Yulu Wang#, Guoming Du#, Yuebin Zhang#, Haiyan Yu, Shujun Liu, Zhaoxing Wang, Xiaochen Ma, Xue Wei, Boting Wen, Zhen Li, Shilong Fan, Fengjiao Xin* Distinct Adjacent Substrate Binding Pocket Regulates the Activity of a Decameric Feruloyl Esterase from Bacteroides thetaiotaomicron. Journal of Agricultural and Food Chemistry, 2024, 72(42): 23554-23566 (IF: 5.7)

6. Shujun Liu#, Lubna Soomro#, Xue Wei#, Xufeng Yuan, Tianyi Gu, Zhen Li, Yulu Wang, Yuming Bao, Fengzhong Wang, Boting Wen*, Fengjiao Xin*, Directed evolution of feruloyl esterase from Lactobacillus acidophilus and its application for ferulic acid production. Bioresource Technology, 2021, 332: 124967 (IF: 11.4)

7. Guoming Du#, Yulu Wang#, Yuebin Zhang#, Haiyan Yu, Shujun Liu, Xiaochen Ma, Hao Cao, Xue Wei, Boting Wen, Zhen Li, Shilong Fan, Huan Zhou, Fengjiao Xin*, Structural insights into the oligomeric effects on catalytic activity of a decameric feruloyl esterase and its application in ferulic acid production. International Journal of Biological Macromolecules, 2023, 253(Pt 1): 126540 (IF: 7.7)

8. Xue Wei#, Yu-lu Wang#, Bo-ting Wen, Shu-jun Liu, Luyao Wang, Lichao Sun, Tian-yi Gu, Zhen Li, Yuming Bao, Shi-long Fan, Huan Zhou, Fengzhong Wang*, Fengjiao Xin*, The α-Helical Cap Domain of a Novel Esterase from Gut Alistipes shahii Shaping the Substrate-Binding Pocket. Journal of Agricultural and Food Chemistry, 2021, 69(21): 6064-6072 (IF: 6.1)

9. Luyao Wang#, Xue Han#, Yulu Wang, Xue Wei, Shujun Liu, Shuli Shao, Shaoqing Yang, Lichao Sun*, Fengjiao Xin*, Rational Design for Broadened Substrate Specificity and Enhanced Activity of a Novel Acetyl Xylan Esterase from Bacteroides thetaiotaomicron. Journal of Agricultural and Food Chemistry, 2021, 69(23): 6665-6675 (IF: 6.1)

10. Hao Cao#, Lichao Sun#, Ying Huang, Xin Liu, Dong Yang, Tengfei Liu, Xiaojing Jia, Boting Wen, Tianyi Gu, Fengzhong Wang*, Fengjiao Xin*, Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester−Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus, ACS Catalysis, 2019, 9, 1739−1747. (IF: 12.2)

代表性科研项目

1. 国家重点研发计划项目（子课题），2023YFF1104004，植物源新食物资源功能组分绿色高效制备关键技术，95万元，2023.12-2027.12，在研；

2. 北京市自然科学基金面上项目，6232035，单序列、双结构域乙酰木聚糖酯酶BT1192的分子内协同催化机制研究，20万元，2023.01-2025.12，在研;

3. 兴安盟科技定向合作项目，菌/酶协同促进玉米加工副产物高值化利用，40万，2024.10-2027.10，在研；

4. 中国农业科学院农产品加工研究所“国之大者”重点科技专项行动，食品生物合成技术构建及人造食品开发，300

5. ，2022.07-2025.06，在研；

6. 国家自然科学基金面上项目，31571963，真菌聚半乳糖醛酸酶诱导RBPG1-SOBIR1复合体活化的分子机制研究，74.4万元，2016.01-2019.12，结题；

7. 国家重点研发计划项目（子课题），2017YFD0400204，食品营养及生物活性物质的健康功能作用，60万元，2017.07-2021.07，结题。

代表性成果

1. 2015年，中国农业科学院“青年英才”；

2. 2016-2019年，中国农业科学院“优秀教师”；

3. 2019-2020年，中国农业科学院“教学名师”；

4. 2023年，中国农业科学院“优秀教师团队”。