专    业：

微生物学

姓    名：

高利娟

职    称：

副教授

研究领域：

肠道益生菌与宿主相互作用机制

邮    箱：

gaolj@sdsmu.edu.cn

电    话：

15053189462

主要社会兼职

山东生物医学工程学会微生态专业委员会委员

代表性论文

1. Lijuan Gao ; Yaru Su; Wenxia Song; Weican Zhang; Qingsheng Qi; Xuemei Lu ; A Type IX Secretion System Substrate Involved in Crystalline Cellulose Degradation by Affecting Crucial Cellulose Binding Proteins in Cytophaga hutchinsonii, Applied and Environmental Microbiology, 2022, 88(2). (IF:4.6).

2. Lijuan Gao ; Yahong Tan; Weican Zhang; Qingsheng Qi; Xuemei Lu ; Cytophaga hutchinsonii SprA and SprT Are Essential Components of the Type IX Secretion System Required for Ca2+ Acquisition, Cellulose Degradation, and Cell Motility, Frontiers in Microbiology, 2021.02, 12. (IF:5.1).

3. Lijuan Gao; Zhiwei Guan; Peng Gao; Weican Zhang; Qingsheng Qi; Xuemei Lu ; Cytophaga hutc hinsonii gldN, Encoding a Core Component of the Type IX Secretion System, Is Essential for Ion Assimilation, Cellulose Degradation, and Cell Motility, Applied and Environmental Microbiology, 2020.05. 86(11).(IF:4.6).

4. Yahong Tan; Wenxia Song; Lijuan Gao; Weican Zhang; Xuemei Lu ; Cytophaga hutchinsoniichu_2177, encoding the O-antigen ligase, is essential for cellulose degradation, Journal of Microbiology, 2022, 60.(IF:3.3)

5. Xifeng Wang, Dong Zhao, Lijuan Gao, Weichan Zhang, Xuemei Lu. Cage-like polyhedrons of DegQ from Cytophaga hutchinsonii show stable proteolytic activity and strong chaperone activity. 2020. April; Biochemical Engineering Journal 159. (IF:3.7)

6. Zhiwei Guan; Ying Wang; Lijuan Gao; Weican Zhang; Xuemei Lu ; Effects of the histone-like protein HU on cellulose degradation and biofilm formation of Cytophaga hutchinsonii, Applied Microbiology and Biotechnology, 2018, 102(15): 6593-6611.  (IF:4.9)

代表性科研项目

1. 国家自然科学基金青年项目，32400091，肠道狄氏副拟杆菌IX分泌系统核心组分PorK的分子作用机制研究，30万元，2025.01-2027.12，在研；

2. 山东省自然科学基金青年项目，ZR2022QC164，应用噬菌体及噬菌体裂解酶治疗铜绿假单胞菌引发感染的研究，15万元，2023.01-2025.12，在研；