专    业：

生物与医药

姓    名：

辛凤姣

职    称：

研究员

研究领域：

食品酶工程，食品合成生物学

邮    箱：

2002hongzhi300163.com

电    话：

15110079693

主要社会兼职

1. 中国农学会食物与营养专业人委员会委员

2. 中国生物工程学会生物农业分会委员

代表性论文

1. 韩雪,王钰璐,于海燕,辛凤姣.多功能木聚糖水解酶的研究及其在食品领域的潜在应用.食品与生物技术学报,2023,42(1):40-54.（通讯作者，北大核心）

2. Wang Y, Du G, Zhang Y, Yu H, Liu S, Wang Z, Ma X, Wei X, Wen B, Li Z, Fan S, Xin F. Distinct Adjacent Substrate Binding Pocket Regulates the Activity of a Decameric Feruloyl Esterase from Bacteroides thetaiotaomicron. J Agric Food Chem. 2024 ;72(42):23554-23566.（通讯作者，SCI-I）

3. Li Z, Sun L, Wang Y, Liu B, Xin F. Construction of a Novel Vanillin-Induced Autoregulating Bidirectional Transport System in a Vanillin-Producing E. coli Cell Factory. J Agric Food Chem. 2024 ;72(26):14809-14820.（通讯作者，SCI-I）

4. Guoming Du, Yulu Wang, Yuebin Zhang, Haiyan Yu, Shujun Liu, Xiaochen Ma, Hao Cao, Xue Wei, Boting Wen, Zhen Li, Shilong Fan, Huan Zhou, Fengjiao Xin, Structural insights into the oligomeric effects on catalytic activity of a decameric feruloyl esterase and its application in ferulic acid production, International Journal of Biological Macromolecules, 2023, 253(1):126540.（通讯作者，SCI-I）

5. Shujun Liu, Boting Wen, Guoming Du, Yulu Wang, Xiaochen Ma, Haiyan Yu, Jingjian Zhang, Shilong Fan, Huan Zhou, Fengjiao Xin, Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH, Food Chemistry, 2023, 403:134436.（通讯作者，SCI-I）

6. Xue Wei, Yulu Wang, Su Zhang, Tianyi Gu, Gabryel Steinmetz, Haiyan Yu, Guoguang Guo, Xin Liu, Shilong Fan, Fengzhong Wang, Yangnan Gu, Fengjiao Xin, Structural analysis of receptor-like kinase SOBIR1 reveals mechanisms that regulate its phosphorylation-dependent activation, Plant Communications, 2022, 3(2):100301.（通讯作者，SCI-I）

7. Haowen Zhang, Boting Wen, Yusi Liu, Guoming Du, Xue Wei, Khandaker Md Sharif Uddin Imam, Huan Zhou, Shilong Fan, Fengzhong Wang, Yulu Wang, Fengjiao Xin, A reverse catalytic triad Asp containing loop shaping a wide substrate binding pocket of a feruloyl esterase from Lactobacillus plantarum, International Journal of Biological Macromolecules, 2021, 184: 92-100.（共同通讯作者，SCI-I）

8. Shujun Liu, Lubna Soomro, Xue Wei, Xufeng Yuan, Tianyi Gu, Zhen Li, Yulu Wang, Yuming Bao, Fengzhong Wang, Boting Wen, Fengjiao Xin,. Directed evolution of feruloyl esterase from Lactobacillus acidophilus and its application for ferulic acid production. Bioresource Technology, 2021, 332: 124967.（共同通讯作者，SCI-I）

9. Wang, L., Han, X., Wang, Y., Wei, X., Liu, S., Shao, S., Yang, S., Sun, L., & Xin, F. Rational Design for Broadened Substrate Specificity and Enhanced Activity of a Novel Acetyl Xylan Esterase from Bacteroides thetaiotaomicron. J Agric Food Chem. 2021;69(23):6665-6675.（共同通讯作者，SCI-I）

10. Wei, X., Wang, Y. L., Wen, B. T., Liu, S. J., Wang, L., Sun, L., Gu, T. Y., Li, Z., Bao, Y., Fan, S. L., Zhou, H., Wang, F., & Xin, F. The α-Helical Cap Domain of a Novel Esterase from Gut Alistipes shahii Shaping the Substrate-Binding Pocket. Journal of agricultural and food chemistry,2021;69(21), 6064–6072.（共同通讯作者，SCI-I）

11. Sun, L., Xin, F., & Alper, H. S. Bio-synthesis of food additives and colorants-a growing trend in future food. Biotechnol Adv. 2021;47:107694.（共同通讯作者，SCI-I）

12. 王璐瑶,韩雪,王凤忠,孙丽超,辛凤姣. 姜黄素类化合物生物合成研究进展. 生物工程学报,2021,37(2):404-417.（通讯作者，北大核心）

13. 张浩雯,曹浩,王钰璐,辛凤姣.人体肠道菌群来源碳水化合物活性酶(CAZYmes)研究进展.生物化学与生物物理进展,2020,47(7):607-625.（通讯作者，北大核心）

代表性科研项目

1. 国家重点研发计划子课题-植物源新食物资源功能组分绿色高效制备关键技术 主持

2. 国家自然科学基金青年项目-双催化结构域乙酰木聚糖酯酶BT1192的分子内协同催化机制研究 主持

3. 国家重点研发子课题-食品营养及生物活性物质的健康功能作用 主持

代表性成果

1. 2022-2023学年优秀教师团队，教学成果奖

2. 2020-2021学年教学名师，教学成果奖

3. 2019-2020学年教学名师，教学成果奖